Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Liver X receptors as potential targets for cancer therapeutics (Review)

23 Oct 2017

Abstract excerpt

Liver X receptors (LXRs) are important members of the nuclear receptor family that were originally determined to function in cholesterol transport and the regulation of immune responses. Synthetic LXR ligands have been developed to treat various diseases including diabetes, Alzheimer's disease and atherosclerosis. Previous studies have suggested that LXRs are also involved in numerous types of cancer and are...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cholesterol and Lipid Metabolism
Share to Drug Transport and Resistance Mechanisms
Share to Sphingolipid Metabolism and Signaling

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 29250170
DOI: 10.3892/ol.2017.7259

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Liver X receptors as potential targets for cancer therapeutics (Review)PMID 29250170Read ↗

The emerging roles of liver X receptors and their ligands in cancerSemantic proximity Read ↗

Targeting liver X receptors in human health: deadlock or promising trail?Semantic proximity Read ↗

Liver X Receptors and their Agonists: Targeting for Cholesterol Homeostasis and Cardiovascular DiseasesSemantic proximity Read ↗

Screening for liver X receptor modulators: Where are we and for what use?Semantic proximity Read ↗

Targeting liver X receptors in inflammationSemantic proximity Read ↗

Emerging Insights into Liver X Receptor α in the Tumorigenesis and Therapeutics of Human CancersSemantic proximity Read ↗

Mechanisms and Therapeutic Advances of PXR in Metabolic Diseases and CancerSemantic proximity Read ↗

The roles of liver X receptor α in inflammation and inflammation‐associated diseasesSemantic proximity Read ↗

Nuclear Receptors as Therapeutic Targets in Liver Disease: Are We There Yet?Semantic proximity Read ↗

The Role of Nuclear Receptors in the Pathogenesis and Treatment of Non-alcoholic Fatty Liver DiseaseSemantic proximity Read ↗

Minireview: liver X receptor beta: emerging roles in physiology and diseases.Semantic proximity Read ↗

Liver-X receptor β-selective agonist CE9A215 regulates Alzheimer’s disease- associated pathology in a 3xTg-AD mouse modelSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.