Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rex1/Zfp42 as an epigenetic regulator for genomic imprinting.

Human molecular genetics - 1 Apr 2011

Kim Jeong Do, Kim Hana, Ekram Muhammad B, Yu Sungryul, Faulk Christopher, Kim Joomyeong

Abstract excerpt

Zfp42/Rex1 (reduced expression gene 1) is a well-known stem-cell marker that has been duplicated from YY1 in the eutherian lineage. In the current study, we characterized the in vivo roles of Rex1 using a mutant mouse line disrupting its transcription. In contrast to the ubiquitous expression of YY1, Rex1 is expressed only during spermatogenesis and early embryogenesis and also in a very limited area of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blastocyst
Share to Chromogranins
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genomic Imprinting

Share to GTP-Binding Protein alpha Subunits, Gs

Share to Kruppel-Like Transcription Factors

Share to Mice, Mutant Strains

Share to Transcription Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 21233130
DOI: 10.1093/hmg/ddr017
PMCID: PMC3049358

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rex1/Zfp42 as an epigenetic regulator for genomic imprinting.PMID 21233130Read ↗

Rex1/Zfp42 is dispensable for pluripotency in mouse ES cells.Semantic proximity Read ↗

Heterozygous loss of ZBTB38 leads to early embryonic lethality in mice via suppressing Nanog and Sox2Semantic proximity Read ↗

Transcriptional regulation of Rex1 (zfp42) in normal prostate epithelial cells and prostate cancer cells.Semantic proximity Read ↗

Enhanced chromatin accessibility contributes to X chromosome dosage compensation in mammals.Semantic proximity Read ↗

REX1 is the critical target of RNF12 in imprinted X chromosome inactivation in miceSemantic proximity Read ↗

Zfp57 mutant ES cell lines directly derived from blastocysts.Semantic proximity Read ↗

Lrh1 can help reprogram sexual cell fate and is required for Sertoli cell development and spermatogenesis in the mouse testisSemantic proximity Read ↗

Dosage compensation in the mouse balances up-regulation and silencing of X-linked genes.Semantic proximity Read ↗

Dnmt3b recruitment through E2F6 transcriptional repressor mediates germ-line gene silencing in murine somatic tissuesSemantic proximity Read ↗

Defects in dosage compensation impact global gene regulation in the mouse trophoblast.Semantic proximity Read ↗

Impaired imprinted X chromosome inactivation is responsible for the skewed sex ratio following in vitro fertilizationSemantic proximity Read ↗

YY1's role in the Peg3 imprinted domain.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.