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Article

Selective disruption of the mammalian secretory apparatus enhances or eliminates calcium current modulation in nerve endings.

Proceedings of the National Academy of Sciences of the United States of America - 29 Apr 2008

Silinsky Eugene M

Abstract excerpt

Modulation of secretion via G protein-coupled receptors (GPCRs) serves an important regulatory function in neuronal and nonneuronal secretory cells. Most secretory cells possess voltage-gated calcium channels, share homologues of the core complex of three proteins (the SNAREs) that constitute the secretory apparatus, and are modulated by GPCR activation. Activators of GPCRs generally inhibit the release of...

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Identifiers

PMID: 18420824
DOI: 10.1073/pnas.0708814105
PMCID: PMC2359788

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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