Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Botulinum Toxin: A Comprehensive Review of Its Molecular Architecture and Mechanistic Action

17 Jan 2025

Abstract excerpt

Botulinum toxin (BoNT), the most potent substance known to humans, likely evolved not to kill but to serve other biological purposes. While its use in cosmetic applications is well known, its medical utility has become increasingly significant due to the intricacies of its structure and function. The toxin's structural complexity enables it to target specific cellular processes with remarkable precision, making...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Botulinum Toxin and Related Neurological Disorders
Share to Hereditary Neurological Disorders
Share to Neurological disorders and treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39859491
DOI: 10.3390/ijms26020777

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Botulinum Toxin: A Comprehensive Review of Its Molecular Architecture and Mechanistic ActionPMID 39859491Read ↗

Challenges in searching for therapeutics against Botulinum NeurotoxinsSemantic proximity Read ↗

Embracing the Versatility of Botulinum Neurotoxins in Conventional and New Therapeutic ApplicationsSemantic proximity Read ↗

Therapeutic Applications of Botulinum Neurotoxins in Veterinary MedicineSemantic proximity Read ↗

Structure and function of tetanus and botulinum neurotoxinsSemantic proximity Read ↗

Botulinum toxin intoxication requires retrograde transport and membrane translocation at the ER in RenVM neuronsSemantic proximity Read ↗

A dileucine in the protease of botulinum toxin A underlies its long-lived neuroparalysis: transfer of longevity to a novel potential therapeutic.Semantic proximity Read ↗

Botulinum Neurotoxins in Central Nervous System: An Overview from Animal Models to Human TherapySemantic proximity Read ↗

A Comprehensive Structural Analysis of Clostridium botulinum Neurotoxin A Cell-Binding Domain from Different SubtypesSemantic proximity Read ↗

Light Chain Diversity among the Botulinum NeurotoxinsSemantic proximity Read ↗

Botulinum neurotoxin C mutants reveal different effects of syntaxin or SNAP-25 proteolysis on neuromuscular transmission.Semantic proximity Read ↗

Botulinum Neurotoxin A1 Signaling in Pain Modulation within Human Sensory NeuronsSemantic proximity Read ↗

Characterization of a membrane binding loop leads to engineering botulinum neurotoxin B with improved therapeutic efficacy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.