Article
Attenuation of retinal endothelial cell migration and capillary morphogenesis in the absence of bcl-2.
American journal of physiology. Cell physiology - 1 Jun 2008
Kondo Shuji, Tang Yixin, Scheef Elizabeth A, Sheibani Nader, Sorenson Christine M
Abstract excerpt
Apoptosis plays a critical role during development and in the maintenance of the vascular system. B-cell leukemia lymphoma 2 (bcl-2) protects endothelial cells (EC) from apoptosis in response to a variety of stimuli. Previous work from this laboratory demonstrated attenuation of postnatal retinal vascular development and retinal neovascularization during oxygen-induced ischemic retinopathy in bcl-2-deficient...
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