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Article

Plastic roles of pericytes in the blood–retinal barrier

16 May 2017

Abstract excerpt

The blood-retinal barrier (BRB) consists of tightly interconnected capillary endothelial cells covered with pericytes and glia, but the role of the pericytes in BRB regulation is not fully understood. Here, we show that platelet-derived growth factor (PDGF)-B/PDGF receptor beta (PDGFRβ) signalling is critical in formation and maturation of BRB through active recruitment of pericytes onto growing retinal vessels....

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PMID: 28508859
DOI: 10.1038/ncomms15296

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