Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impaired pericyte recruitment and abnormal retinal angiogenesis as a result of angiopoietin-2 overexpression

1 Jan 2007

Abstract excerpt

Angiopoietin-2 (Ang2) is among the relevant growth factors induced by hypoxia and plays an important role in the initiation of retinal neovascularizations. Ang2 is also involved in incipient diabetic retinopathy, as it may cause pericyte loss. To investigate the impact of Ang2 on developmental and hypoxia-induced angiogenesis, we used a transgenic mouse line overexpressing human Ang2 in the mouse retina....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiogenesis and VEGF in Cancer
Share to Cancer, Hypoxia, and Metabolism
Share to Lipid metabolism and disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 17200776
DOI: 10.1160/th06-05-0277

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impaired pericyte recruitment and abnormal retinal angiogenesis as a result of angiopoietin-2 overexpressionPMID 17200776Read ↗

Pericytes and the Pathogenesis of Diabetic RetinopathySemantic proximity Read ↗

Angiogenesis and Eye DiseaseSemantic proximity Read ↗

VEGFR1–mediated pericyte ablation links VEGF and PlGF to cancer-associated retinopathySemantic proximity Read ↗

Hypoxia-Induced Retinal Neovascularization in Zebrafish Embryos: A Potential Model of Retinopathy of PrematuritySemantic proximity Read ↗

Plastic roles of pericytes in the blood–retinal barrierSemantic proximity Read ↗

Roles of Hypoxia Response in Retinal Development and PathophysiologySemantic proximity Read ↗

Identification of Genes and Pathways Involved in Retinal Neovascularization by Microarray Analysis of Two Animal Models of Retinal AngiogenesisSemantic proximity Read ↗

Repeated treatment with VEGF receptor inhibitors induces phenotypic changes in endothelial cells and pericytes in the rat retina.Semantic proximity Read ↗

Argon Laser Photocoagulation–Induced Modification of Gene Expression in the RetinaSemantic proximity Read ↗

Retinal angiogenesis in development and diseaseSemantic proximity Read ↗

Müller cell‐derived VEGF is a significant contributor to retinal neovascularizationSemantic proximity Read ↗

Revisiting the mouse model of oxygen-induced retinopathySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.