Article

Targeting endothelial ERG to mitigate vascular regression and neuronal ischemia in retinopathies

2024-12-27

Abstract excerpt

<h4>ABSTRACT</h4> Retinopathy of prematurity (ROP) and diabetic retinopathy (DR) are ocular disorders in which a loss of retinal vasculature leads to ischemia followed by a compensatory neovascularization response. In mice, this is modeled using oxygen-induced retinopathy (OIR), whereby neonatal animals are transiently housed under hyperoxic conditions that result in central retina vessel regression and subsequen...

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Literature Corpus work: 5a3f04c9-f0dc-5d20-aab5-855764a65eea
DOI: 10.1101/2024.12.27.630529

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