Article
Genome-wide analysis of abnormal H3K9 acetylation in cloned mice.
PloS one - 9 Apr 2008
Suzuki Takahiro, Kondo Shinji, Wakayama Teruhiko, Cizdziel Paul E, Hayashizaki Yoshihide
Abstract excerpt
Somatic nuclear transfer is a cloning technique that shows great promise in the application to regenerative medicine. Although cloned animals are genetically identical to their donor counterparts, abnormalities in phenotype and gene expression are frequently observed. One hypothesis is that the cause of these abnormalities is due to epigenetic aberration. In this report, we focused our analysis on the acetylation...
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