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Histone proteoform analysis reveals epigenetic changes in adult mouse brown adipose tissue in response to cold stress

27 Apr 2024

Abstract excerpt

BACKGROUND: Regulation of the thermogenic response by brown adipose tissue (BAT) is an important component of energy homeostasis with implications for the treatment of obesity and diabetes. Our preliminary analyses of RNA-Seq data uncovered many nodes representing epigenetic modifiers that are altered in BAT in response to chronic thermogenic activation. Thus, we hypothesized that chronic thermogenic activation...

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Share to Adipokines, Inflammation, and Metabolic Diseases
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PMID: 38678237
DOI: 10.1186/s13072-024-00536-8

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