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Recent advancements in cloning by somatic cell nuclear transfer

19 Nov 2012

Abstract excerpt

Somatic cell nuclear transfer (SCNT) cloning is the sole reproductive engineering technology that endows the somatic cell genome with totipotency. Since the first report on the birth of a cloned sheep from adult somatic cells in 1997, many technical improvements in SCNT have been made by using different epigenetic approaches, including enhancement of the levels of histone acetylation in the chromatin of the...

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PMID: 23166393
DOI: 10.1098/rstb.2011.0329

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