Article
Natural variation of histone modification and its impact on gene expression in the rat genome.
Genome research - 1 Jun 2014
Rintisch Carola, Heinig Matthias, Bauerfeind Anja, Schafer Sebastian, Mieth Christin, Patone Giannino, Hummel Oliver, Chen Wei, Cook Stuart, Cuppen Edwin, Colomé-Tatché Maria, Johannes Frank, Jansen Ritsert C, Neil Helen, Werner Michel, Pravenec Michal, Vingron Martin, Hubner Norbert
Abstract excerpt
Histone modifications are epigenetic marks that play fundamental roles in many biological processes including the control of chromatin-mediated regulation of gene expression. Little is known about interindividual variability of histone modification levels across the genome and to what extent they are influenced by genetic variation. We annotated the rat genome with histone modification maps, identified...
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