Article
Association between AKT1 gene and Parkinson's disease: a protective haplotype.
Neuroscience letters - 9 May 2008
Xiromerisiou Georgia, Hadjigeorgiou Georgios M, Papadimitriou Alexandros, Katsarogiannis Evaggelos, Gourbali Vasiliki, Singleton Andrew B
Abstract excerpt
Variation in AKT1 has been associated with schizophrenia, bipolar disease and type II diabetes. The aim of the present study was to investigate the potential role of variability within AKT1 as a risk factor for Parkinson's disease (PD). We performed a case-control association analysis of AKT1 in a Greek cohort of PD using four tagging SNPs and five constructed haplotypes. To assess the structure of this locus in...
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