Article
Association analysis of AKT1 and schizophrenia in a UK case control sample.
Schizophrenia research - 1 Jul 2007
Norton Nadine, Williams Hywel J, Dwyer Sarah, Carroll Liam, Peirce Tim, Moskvina Valentina, Segurado Ricardo, Nikolov Ivan, Williams Nigel M, Ikeda Masashi, Iwata Nakao, Owen Michael J, O'Donovan Michael C
Abstract excerpt
AKT1 (V-akt murine thyoma viral oncogene homolog 1) is involved in intracellular signalling pathways postulated as of aetiological importance in schizophrenia. Markers in the AKT1 gene have also recently been associated with schizophrenia in two samples of European origin and in Japanese and Iranian samples. Aiming to replicate these findings, we examined ten SNPs spanning AKT1 in a UK case-control sample...
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