Article
Genetic studies of the protein kinase AKT1 in Parkinson's disease.
Neuroscience letters - 21 Aug 2011
Ran Caroline, Westerlund Marie, Anvret Anna, Willows Thomas, Sydow Olof, Galter Dagmar, Belin Andrea Carmine
Abstract excerpt
The protein kinase AKT1 belongs to the Akt family and is a potent mediator of cell growth and survival and fully activated when phosphorylated. The AKT family has been found to be phosphorylated to a lesser extent in the dopaminergic cells of Parkinson's disease patients compared to control individuals, which might influence cell survival. Several publications support the implication of AKT1 in disorders of the...
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