Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of AKT1 gene variants and protein expression in both schizophrenia and bipolar disorder.

Genes, brain, and behavior - 1 Jul 2010

Karege F, Perroud N, Schürhoff F, Méary A, Marillier G, Burkhardt S, Ballmann E, Fernandez R, Jamain S, Leboyer M, La Harpe R, Malafosse A

Abstract excerpt

The AKT1 gene has been associated with the genetic aetiology of schizophrenia. Following the overlap model of bipolar disorder and schizophrenia, we aimed to investigate AKT1 genetic variants and protein expression in both diseases. A total of 679 subjects with European ancestry were included: 38...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bipolar Disorder
Share to Brain
Share to Genetic Association Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Haplotypes

Share to Proto-Oncogene Proteins c-akt

Share to Reference Values

Share to Schizophrenia

Share to Statistics, Nonparametric

Source

Identifiers

PMID: 20214684
DOI: 10.1111/j.1601-183X.2010.00578.x

Genes

AKT1
AKT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20214684-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of AKT1 gene variants and protein expression in both schizophrenia and bipolar disorder.PMID 20214684Read ↗

Genetic association of the AKT1 gene with schizophrenia in a British population.Semantic proximity Read ↗

Further evidence for association of variants in the AKT1 gene with schizophrenia in a sample of European sib-pair families.Semantic proximity Read ↗

AKT1 is associated with schizophrenia across multiple symptom dimensions in the Irish study of high density schizophrenia families.Semantic proximity Read ↗

Genetic overlap between schizophrenia and bipolar disorder: a study with AKT1 gene variants and clinical phenotypes.Semantic proximity Read ↗

Association analysis of AKT1 and schizophrenia in a UK case control sample.Semantic proximity Read ↗

No association between AKT1 gene variants and schizophrenia: a Malaysian case-control study and meta-analysis.Semantic proximity Read ↗

Association of AKT1 haplotype with the risk of schizophrenia in Iranian population.Semantic proximity Read ↗

Association of AKT1 with schizophrenia confirmed in a Japanese population.Semantic proximity Read ↗

Association of AKT1 gene polymorphisms with risk of schizophrenia and with response to antipsychotics in the Chinese population.Semantic proximity Read ↗

Marked reduction of AKT1 expression and deregulation of AKT1-associated pathways in peripheral blood mononuclear cells of schizophrenia patients.Semantic proximity Read ↗

Failure to support a genetic contribution of AKT1 polymorphisms and altered AKT signaling in schizophrenia.Semantic proximity Read ↗

No association between AKT1 polymorphism and schizophrenia: a case-control study in a Korean population and a meta-analysis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.