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Article

Association of AKT1 with schizophrenia confirmed in a Japanese population.

Biological psychiatry - 1 Nov 2004

Ikeda Masashi, Iwata Nakao, Suzuki Tatsuyo, Kitajima Tsuyoshi, Yamanouchi Yoshio, Kinoshita Yoko, Inada Toshiya, Ozaki Norio

Abstract excerpt

BACKGROUND: Abnormality of the V-akt murine thymoma viral oncogene homologue 1 (AKT1) may be a predisposing factor in schizophrenia. Recent evidence supporting this hypothesis showed decreased AKT1 protein levels in patients with schizophrenia and significant association of AKT1 haplotypes accord...

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Source

Identifiers

PMID: 15522255
DOI: 10.1016/j.biopsych.2004.07.023

Genes

AKT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15522255-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of AKT1 with schizophrenia confirmed in a Japanese population.PMID 15522255Read ↗

No association between AKT1 polymorphism and schizophrenia: a case-control study in a Korean population and a meta-analysis.Semantic proximity Read ↗

Association analysis of AKT1 and schizophrenia in a UK case control sample.Semantic proximity Read ↗

Genetic association of the AKT1 gene with schizophrenia in a British population.Semantic proximity Read ↗

Association of AKT1 gene polymorphisms with risk of schizophrenia and with response to antipsychotics in the Chinese population.Semantic proximity Read ↗

Absence of significant associations between four AKT1 SNP markers and schizophrenia in the Taiwanese population.Semantic proximity Read ↗

No association between AKT1 gene variants and schizophrenia: a Malaysian case-control study and meta-analysis.Semantic proximity Read ↗

Further evidence for association of variants in the AKT1 gene with schizophrenia in a sample of European sib-pair families.Semantic proximity Read ↗

Association of AKT1 haplotype with the risk of schizophrenia in Iranian population.Semantic proximity Read ↗

Association of AKT1 gene variants and protein expression in both schizophrenia and bipolar disorder.Semantic proximity Read ↗

Positive association of AKT1 haplotype to Japanese methamphetamine use disorder.Semantic proximity Read ↗

AKT1 is associated with schizophrenia across multiple symptom dimensions in the Irish study of high density schizophrenia families.Semantic proximity Read ↗

Failure to support a genetic contribution of AKT1 polymorphisms and altered AKT signaling in schizophrenia.Semantic proximity Read ↗

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