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Article

Further evidence for association of variants in the AKT1 gene with schizophrenia in a sample of European sib-pair families.

Biological psychiatry - 15 Sept 2005

Schwab Sibylle G, Hoefgen Barbara, Hanses Claudia, Hassenbach Margitta Borrmann, Albus Margot, Lerer Bernard, Trixler Matyas, Maier Wolfgang, Wildenauer Dieter B

Abstract excerpt

BACKGROUND: Involvement of AKT signaling pathways in schizophrenia has been recently suggested, on the basis of several lines of evidence. In addition to impairment of protein-levels and phosphorylation levels in the pathway, association of DNA sequence variants in the AKT1 gene with schizophrenia has been detected in a family sample. METHODS: We investigated the reported association of DNA sequence variants in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16026766
DOI: 10.1016/j.biopsych.2005.05.005

Genes

AKT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

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Further evidence for association of variants in the AKT1 gene with schizophrenia in a sample of European sib-pair families.PMID 16026766Read ↗

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Association of AKT1 gene variants and protein expression in both schizophrenia and bipolar disorder.Semantic proximity Read ↗

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Association of AKT1 with schizophrenia confirmed in a Japanese population.Semantic proximity Read ↗

AKT1 is associated with schizophrenia across multiple symptom dimensions in the Irish study of high density schizophrenia families.Semantic proximity Read ↗

Association of AKT1 haplotype with the risk of schizophrenia in Iranian population.Semantic proximity Read ↗

Association between AKT1 gene and Parkinson's disease: a protective haplotype.Semantic proximity Read ↗

No association between AKT1 gene variants and schizophrenia: a Malaysian case-control study and meta-analysis.Semantic proximity Read ↗

No association between AKT1 polymorphism and schizophrenia: a case-control study in a Korean population and a meta-analysis.Semantic proximity Read ↗

Absence of significant associations between four AKT1 SNP markers and schizophrenia in the Taiwanese population.Semantic proximity Read ↗

Association of AKT1 gene polymorphisms with risk of schizophrenia and with response to antipsychotics in the Chinese population.Semantic proximity Read ↗

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