Article
No association between AKT1 gene variants and schizophrenia: a Malaysian case-control study and meta-analysis.
Psychiatry research - 30 Oct 2013
Loh Han Chern, Chow Tze Jen, Tang Pek Yee, Yong Hoi Sen
Abstract excerpt
We aim to replicate AKT1 gene variants studies using Malaysian samples. Seven AKT1 single nucleotide polymorphisms (SNPs) were studied in 417 patients and 429 controls. Haplotype showed significant association (p=0.036) with schizophrenia, especially in Malays and Indians. Meta-analysis of rs2494732 showed significant association worldwide (p=0.018) and in Asians (p=0.023).
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