Association of AKT1 haplotype with the risk of schizophrenia in Iranian population.

doi:10.1002/ajmg.b.30291

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Association of AKT1 haplotype with the risk of schizophrenia in Iranian population.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Jun 2006

Bajestan Sepideh N, Sabouri Amir H, Nakamura Masayuki, Takashima Hiroshi, Keikhaee Mohammad R, Behdani Fatemeh, Fayyazi Mohammad R, Sargolzaee Mohammad R, Bajestan Mahboobeh N, Sabouri Zahra, Khayami Esmaeil, Haghighi Sima, Hashemi Susan B, Eiraku Nobutaka, Tufani Hamid, Najmabadi Hossein, Arimura Kimiyoshi, Sano Akira, Osame Mitsuhiro

Abstract excerpt

AKT-glycogen synthase kinase 3beta (GSK3beta) signaling is a target of lithium and has been implicated in the pathogenesis of mood disorders and schizophrenia. AKT1 protein level is decreased in the peripheral lymphocytes and brains of schizophrenic patients. The SNP2/3/4 TCG haplotype of AKT1 was associated with schizophrenia in patients with Northern European origin. In the present study, we genotyped five...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Haplotypes

Share to Iran

Share to Linkage Disequilibrium

Share to Proto-Oncogene Proteins c-akt

Share to Risk Factors

Share to Schizophrenia

Source

Open in PubMed

Identifiers

PMID: 16583435
DOI: 10.1002/ajmg.b.30291

Genes

AKT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of AKT1 haplotype with the risk of schizophrenia in Iranian population.PMID 16583435Read ↗

Association of AKT1 gene polymorphisms with risk of schizophrenia and with response to antipsychotics in the Chinese population.Semantic proximity Read ↗

No association between AKT1 polymorphism and schizophrenia: a case-control study in a Korean population and a meta-analysis.Semantic proximity Read ↗

Association of AKT1 with schizophrenia confirmed in a Japanese population.Semantic proximity Read ↗

No association between AKT1 gene variants and schizophrenia: a Malaysian case-control study and meta-analysis.Semantic proximity Read ↗

Genetic association of the AKT1 gene with schizophrenia in a British population.Semantic proximity Read ↗

Association analysis of AKT1 and schizophrenia in a UK case control sample.Semantic proximity Read ↗

Association of AKT1 gene variants and protein expression in both schizophrenia and bipolar disorder.Semantic proximity Read ↗

Positive association of AKT1 haplotype to Japanese methamphetamine use disorder.Semantic proximity Read ↗

Further evidence for association of variants in the AKT1 gene with schizophrenia in a sample of European sib-pair families.Semantic proximity Read ↗

Absence of significant associations between four AKT1 SNP markers and schizophrenia in the Taiwanese population.Semantic proximity Read ↗

Genetic study of eight AKT1 gene polymorphisms and their interaction with DRD2 gene polymorphisms in tardive dyskinesia.Semantic proximity Read ↗

AKT1 is associated with schizophrenia across multiple symptom dimensions in the Irish study of high density schizophrenia families.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.