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Article

[Inactivation of the VHL gene in sporadic clear cell renal cancer].

Molekuliarnaia biologiia - 1 Jan 2000

Mikhaĭlenko D S, Kurynin R B, Popov A M, Kariakin O B, Enikeev M E, Aliaev Iu G, Nemtsova M V, Zaletaev D V

Abstract excerpt

Renal cell carcinoma is the most common variant of the kidney cancer, which accounts approximately 75% patients with this disease. The majority of those tumors are characterized by inactivation of the VHL gene suppressor as a result of mutations, allelic deletions and/or methylation. We have conducted the complex molecular-genetic analysis of 64 samples obtained from patients with the clear cell renal cancer. VHL...

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Share to Alleles
Share to Carcinoma, Renal Cell
Share to DNA Methylation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Kidney Neoplasms

Share to Neoplasm Staging

Share to Polymorphism, Single-Stranded Conformational

Share to Von Hippel-Lindau Tumor Suppressor Protein

Source

Identifiers

PMID: 18389622

Genes

VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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