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Article

VHL tumor suppressor gene alterations associated with good prognosis in sporadic clear-cell renal carcinoma.

Journal of the National Cancer Institute - 16 Oct 2002

Yao Masahiro, Yoshida Minoru, Kishida Takeshi, Nakaigawa Noboru, Baba Masaya, Kobayashi Kazuki, Miura Takeshi, Moriyama Masatoshi, Nagashima Yoji, Nakatani Yukio, Kubota Yoshinobu, Kondo Kei-Ichi

Abstract excerpt

BACKGROUND: Somatic alteration of the von Hippel-Lindau disease tumor suppressor gene (VHL) is one of the most common genetic changes observed in the sporadic, clear-cell subtype of renal cell carcinoma (RCC). However, the prognostic utility of VHL mutations has not been examined. The purpose of this study was to explore the association between VHL mutations and the risk of death from sporadic clear-cell RCC....

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Share to Adenocarcinoma, Clear Cell
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12381710
DOI: 10.1093/jnci/94.20.1569

Genes

VHL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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