Article
[Frequent somatic mutations of the von Hippel-Lindau (VHL) tumor suppressor gene and its meaning in sporadic human renal clear cell carcinoma].
Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences - 1 Apr 2004
Gong Kan, Zhang Ning, Guo Hong-feng, Zhang Zhi-wen, Xin Dian-qi, Na Yan-qun
Abstract excerpt
OBJECTIVE: To investigate the mutation of VHL gene, an important tumor suppressor gene in primary sporadic human renal cell carcinoma (RCC) and analyse its relationships with pathological stage and grade of renal cell carcinoma. METHODS: We analyzed 57 cases of primary sporadic Chinese renal clea...
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