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Article

COX-2 gene promoter polymorphism and coronary artery disease in middle-aged men: the Helsinki sudden death study.

Mediators of inflammation - 1 Jan 2008

Huuskonen Kati H, Kunnas Tarja A, Tanner Minna M, Mikkelsson Jussi, Ilveskoski Erkki, Karhunen Pekka J, Nikkari Seppo T

Abstract excerpt

Cyclooxygenase (COX) catalyzes formation of prostaglandins that contribute to the inflammation in atherosclerosis. Our objective was to study whether the functional C variant of the -765G-->C polymorphism in the human COX-2 gene associates with the severity of coronary atherosclerosis measured at the coronary artery level. The Helsinki sudden death study autopsy material (n = 300) comprised of Finnish men who...

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Identifiers

PMID: 18385811
DOI: 10.1155/2008/289453
PMCID: PMC2276816

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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