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Article

Polymorphisms within the tumor necrosis factor locus and prevalence of coronary artery disease in middle-aged men.

Atherosclerosis - 15 Feb 2001

Keso T, Perola M, Laippala P, Ilveskoski E, Kunnas T A, Mikkelsson J, Penttilä A, Hurme M, Karhunen P J

Abstract excerpt

Tumor necrosis factor (TNF) is an important cytokine in the inflammation process of atherosclerosis and is also involved in lipid metabolism. Two biallelic polymorphisms within TNF gene locus-TNFA at the position -308 in the promoter region of the TNF gene and TNFB in the first intron of the lymphotoxin-alpha (LT-alpha) have been reported to be associated with TNF production and with susceptibility to...

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Source

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PMID: 11257271
DOI: 10.1016/s0021-9150(00)00602-x

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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