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Article

The COX-2 G/C -765 polymorphism may modulate the occurrence of cerebrovascular ischemia.

Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Mar 2006

Colaizzo Donatella, Fofi Laura, Tiscia Gianluca, Guglielmi Renzo, Cocomazzi Nicola, Prencipe Massimiliano, Margaglione Maurizio, Toni Danilo

Abstract excerpt

In the atherosclerotic plaque, cyclooxygenase-2 (COX-2) catalyzes prostaglandin E formation, which acts as a pro-atherogenic factor. A polymorphism, G/C -765, within the COX-2 promoter region modulates gene expression and the risk of cerebrovascular disease. We have evaluated the relation between COX-2 G/C -765 genotypes and the occurrence of cerebrovascular ischemia. We evaluated the COX-2 G/C -765 polymorphism...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16479190
DOI: 10.1097/01.mbc.0000214706.88621.da

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The COX-2 G/C -765 polymorphism may modulate the occurrence of cerebrovascular ischemia.PMID 16479190Read ↗

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