Article
Polymorphisms of TGFβ-1 and TGFBR2 in relation to coronary artery disease in a Chinese population.
Clinical biochemistry - 1 Aug 2016
Yang Minjun, Zhu Min, Tang Lijiang, Zhu Huanhuan, Lu Yifei, Xu Baohui, Jiang Jianjun, Chen Xiaofeng
Abstract excerpt
BACKGROUND AND AIM: TGF-β1 has been previously reported to be involved in the pathogenesis of atherosclerosis. The aim of the present study was to assess whether functional gene polymorphisms of TGF-β1 and its key receptor TGF-β receptor type II (TGFBR2) contribute as risk factors to the onset and severity of atherosclerotic coronary artery disease (CAD). DESIGN AND METHODS: A total of 605 patients who underwent...
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