Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pharmacokinetic genes do not influence response or tolerance to citalopram in the STAR*D sample.

PloS one - 2 Apr 2008

Peters Eric J, Slager Susan L, Kraft Jeffrey B, Jenkins Greg D, Reinalda Megan S, McGrath Patrick J, Hamilton Steven P

Abstract excerpt

BACKGROUND: We sought to determine whether clinical response or tolerance to the Selective Serotonin Reuptake Inhibitor (SSRI) citalopram is associated with genetic polymorphisms in potentially relevant pharmacokinetic enzymes. METHODOLOGY: We used a two-stage case-control study design in which we split the sample of 1,953 subjects from the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Citalopram
Share to Clinical Trials as Topic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cytochrome P-450 Enzyme System

Share to Depression

Share to Drug Resistance

Share to Drug Tolerance

Share to Remission Induction

Share to Selective Serotonin Reuptake Inhibitors

Source

Open in PubMed Open full text

Identifiers

PMID: 18382661
DOI: 10.1371/journal.pone.0001872
PMCID: PMC2268970

Genes

ABCB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pharmacokinetic genes do not influence response or tolerance to citalopram in the STAR*D sample.PMID 18382661Read ↗

Genome-wide pharmacogenomic study of citalopram-induced side effects in STAR*D.Semantic proximity Read ↗

CYP2C19 variation and citalopram response.Semantic proximity Read ↗

Analysis of association between the serotonin transporter and antidepressant response in a large clinical sample.Semantic proximity Read ↗

Pharmacogenetics studies in STAR*D: strengths, limitations, and results.Semantic proximity Read ↗

Inclusion of genetic variants in an ensemble of gradient boosting decision trees does not improve the prediction of citalopram treatment response.Semantic proximity Read ↗

A genomewide association study of citalopram response in major depressive disorder.Semantic proximity Read ↗

Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment.Semantic proximity Read ↗

Genome-wide association studies of antidepressant outcome: a brief review.Semantic proximity Read ↗

SSRI response in depression may be influenced by SNPs in HTR1B and HTR1A.Semantic proximity Read ↗

Genetic predictors of antidepressant side effects: a grouped candidate gene approach in the Genome-Based Therapeutic Drugs for Depression (GENDEP) study.Semantic proximity Read ↗

Resequencing of serotonin-related genes and association of tagging SNPs to citalopram response.Semantic proximity Read ↗

Genetic and clinical predictors of sexual dysfunction in citalopram-treated depressed patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.