Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-wide association studies of antidepressant outcome: a brief review.

Progress in neuro-psychopharmacology & biological psychiatry - 15 Aug 2011

Laje Gonzalo, McMahon Francis J

Abstract excerpt

Genome-wide association studies (GWAS) of antidepressant treatment outcome have been at the forefront of psychiatric pharmacogenetics. Such studies may ultimately help match medications with patients, maximizing efficacy while minimizing adverse effects. The hypothesis-free approach of the GWAS has the advantage of interrogating genes that otherwise would have not been considered as candidates due to our limited...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Depressive Disorder
Share to Antidepressive Agents
Share to Depression

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Depressive Disorder, Major

Share to Genome-Wide Association Study

Share to Genotype

Share to Phenotype

Share to Treatment Outcome

Source

Open in PubMed Open full text

Identifiers

PMID: 21115088
DOI: 10.1016/j.pnpbp.2010.11.031
PMCID: PMC3125482

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide association studies of antidepressant outcome: a brief review.PMID 21115088Read ↗

A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression.Semantic proximity Read ↗

Common genetic variation and antidepressant efficacy in major depressive disorder: a meta-analysis of three genome-wide pharmacogenetic studies.Semantic proximity Read ↗

Pharmacogenomics with antidepressants in the STAR*D study.Semantic proximity Read ↗

Genome-wide association studies in pharmacogenomics of antidepressants.Semantic proximity Read ↗

Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment.Semantic proximity Read ↗

Antidepressant treatment response is modulated by genetic and environmental factors and their interactionsSemantic proximity Read ↗

Pharmacogenetics of antidepressant response: a polygenic approachSemantic proximity Read ↗

Genome-wide meta-analyses of non-response to antidepressants provide insights into underlying molecular genetics and suggest potential pharmacotherapies.Semantic proximity Read ↗

Pharmacogenomics of antidepressant drugs.Semantic proximity Read ↗

Genetic predictors of response to serotonergic and noradrenergic antidepressants in major depressive disorder: a genome-wide analysis of individual-level data and a meta-analysis.Semantic proximity Read ↗

New insights into the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation.Semantic proximity Read ↗

Antidepressant pharmacogeneticsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.