Article
Genome-wide pharmacogenomic study of citalopram-induced side effects in STAR*D.
Translational psychiatry - 3 Jul 2012
Adkins D E, Clark S L, Åberg K, Hettema J M, Bukszár J, McClay J L, Souza R P, van den Oord E J C G
Abstract excerpt
Affecting about 1 in 12 Americans annually, depression is a leading cause of the global disease burden. While a range of effective antidepressants are now available, failure and relapse rates remain substantial, with intolerable side effect burden the most commonly cited reason for discontinuation. Thus, understanding individual differences in susceptibility to antidepressant therapy side effects will be...
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