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Article

Genetic and clinical predictors of sexual dysfunction in citalopram-treated depressed patients.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jun 2009

Perlis Roy H, Laje Gonzalo, Smoller Jordan W, Fava Maurizio, Rush A John, McMahon Francis J

Abstract excerpt

Sexual dysfunction is a major contributor to treatment discontinuation and nonadherence among patients treated with selective serotonin reuptake inhibitors (SSRIs). The mechanisms by which depressive symptoms in general, as well as SSRI exposure in particular, may worsen sexual function are not known. We examined genetic polymorphisms, including those of the serotonin and glutamate systems, for association with...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19295509
DOI: 10.1038/npp.2009.4
PMCID: PMC9990953

Genes

GRIA1
GRIA3
GRIK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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