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Article

Analysis of association between the serotonin transporter and antidepressant response in a large clinical sample.

Biological psychiatry - 15 Mar 2007

Kraft Jeffrey B, Peters Eric J, Slager Susan L, Jenkins Greg D, Reinalda Megan S, McGrath Patrick J, Hamilton Steven P

Abstract excerpt

BACKGROUND: SLC6A4 encodes the serotonin transporter, the protein primarily responsible for the termination of serotonin neurotransmission. Because many antidepressants inhibit the transporter, it has been the focus of intense pharmacogenetic analysis. We sought to replicate our previous findings that SLC6A4 is associated with response to a selective serotonin reuptake inhibitor (SSRI) in a large case-control...

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Source

Identifiers

PMID: 17123473
DOI: 10.1016/j.biopsych.2006.07.017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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