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Article

A commonly occurring polymorphism upstream of the estrogen receptor alpha alters transcription and is associated with increased HDL.

Atherosclerosis - 1 Aug 2008

Figtree Gemma A, Grieve Stuart M, Speller Bridget, Geiger Mary-Jane, Robinson Bruce G, Channon Keith M, Ragoussis Jiannis, Collins Peter, Watkins Hugh

Abstract excerpt

OBJECTIVE: Given the role of estrogen in the regulation of lipid metabolism, we screened for functional polymorphisms in the estrogen receptor alpha (ER*), and examined for their influence on serum cholesterol. METHODS AND RESULTS: We identified a novel C>T polymorphism (ERNE-145), with a minor a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 18367190
DOI: 10.1016/j.atherosclerosis.2008.02.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18367190-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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