Article
Association of estrogen receptor gene variants (ESR1 and ESR2) with polycystic ovary syndrome in Tunisia.
Gene - 30 May 2020
Douma Zeineb, Dallel Meriem, Bahia Weal, Ben Salem Assila, Hachani Ben Ali Faten, Almawi Wassim Y, Lautier Corinne, Haydar Sara, Grigorescu Florin, Mahjoub Touhemi
Abstract excerpt
SNV (single nucleotide variation) in estrogen receptor (ESR1 and ESR2) genes are susceptibility markers for complex diseases, such as cancer, metabolic disorders and women infertility. We explored six widely used SNVs in ESR1 (rs2234693, rs9340799, rs3798577, rs3020314) and ESR2 (rs1256049, ) in polycystic ovary syndrome (PCOS) in women from Tunisia (n = 254) compared to controls (n = 170). Genotyping...