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Article

Mutation of the follicle-stimulating hormone receptor gene 5'-untranslated region associated with female hypertension.

Hypertension (Dallas, Tex. : 1979) - 1 Sept 2006

Nakayama Tomohiro, Kuroi Nobuhiro, Sano Morihiko, Tabara Yasuharu, Katsuya Tomohiro, Ogihara Toshio, Makita Yoshio, Hata Akira, Yamada Michiko, Takahashi Norio, Hirawa Nobuhito, Umemura Satoshi, Miki Tetsuro, Soma Masayoshi

Abstract excerpt

Inactivating mutations in the follicle-stimulating hormone receptor (FSHR) gene have been reported to cause hereditary hypergonadotropic ovarian failure. It has been found recently that the FSHR knockout mouse exhibits hypertension. The aim of the present study was to investigate the association between polymorphisms in the human FSHR gene and essential hypertension (EH) by using single nucleotide polymorphisms...

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Identifiers

PMID: 16864747
DOI: 10.1161/01.HYP.0000233877.84343.d7

Genes

FSHR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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