Article
The genetic contribution to human T-cell receptor repertoire.
Immunology - 1 Oct 1991
Loveridge J A, Rosenberg W M, Kirkwood T B, Bell J I
Abstract excerpt
Recent studies in mice have highlighted the importance of polymorphic genetic loci such as the major histocompatibility complex (MHC) or minor lymphocyte-stimulating antigen (Mls) in determining the nature of the peripheral T-cell receptor (TcR) population. As our knowledge of the equivalent process in humans is incomplete, we have utilized a modification of the polymerase chain reaction (PCR) to determine the...
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