Article
The human T-cell receptor beta-chain repertoire: longitudinal fluctuations and assessment in MHC matched populations.
Immunogenetics - 1 Jan 1993
Usuku K, Joshi N, Hatem C J, Alper C A, Schoenfeld D A, Hauser S L
Abstract excerpt
The influence of the environment and of the major histocompatibility complex (MHC) in shaping the human T-cell receptor beta-chain variable region (TCRBV) repertoire has not been systematically studied. Here, expression of TCRBV gene families was estimated by a sensitive polymerase chain reaction (PCR)-based method. Serial studies of peripheral blood, performed at 2-week intervals over a 3-month period, revealed...
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