Influence of coding region polymorphism on the peripheral expression of a human TCR V beta gene.

Article

Influence of coding region polymorphism on the peripheral expression of a human TCR V beta gene.

Journal of immunology (Baltimore, Md. : 1950) - 1 Feb 1994

Vissinga C S, Charmley P, Concannon P

Abstract excerpt

A number of human TCR V beta gene segments are reported to be polymorphic, with alleles differing by one or a small number of amino acid substitutions. In the absence of detailed structural information regarding the interaction of specific positions in the TCR with Ag or MHC, the significance of...

Topics

Alleles
Base Sequence
DNA Primers
Female
Gene Expression
Haplotypes
Humans
Lymphocyte Activation
Male
Molecular Sequence Data
Pedigree
Polymorphism, Genetic
RNA, Messenger
Receptors, Antigen, T-Cell, alpha-beta

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