Article
Melanocyte-lineage expression of Cre recombinase using Mitf regulatory elements.
Pigment cell & melanoma research - 1 Feb 2008
Alizadeh Azita, Fitch Karen R, Niswender Colleen M, McKnight G Stanley, Barsh Gregory S
Abstract excerpt
Manipulation of gene expression in melanocytes is an important tool for studying pigment cell biology. We constructed transgenic mice in which Cre recombinase was placed under the control of regulatory elements from the Microphthalmia-associated transcriptional factor (Mitf) gene using bacterial artificial chromosome (BAC). Bacterial artificial chromosome that contained either 50 or 108 kb DNA 5' to the...
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