Article
The role of MITF phosphorylation sites during coat color and eye development in mice analyzed by bacterial artificial chromosome transgene rescue.
Genetics - 1 Oct 2009
Bauer Georg L, Praetorius Christian, Bergsteinsdóttir Kristín, Hallsson Jón H, Gísladóttir Bryndís K, Schepsky Alexander, Swing Deborah A, O'Sullivan T Norene, Arnheiter Heinz, Bismuth Keren, Debbache Julien, Fletcher Colin, Warming Søren, Copeland Neal G, Jenkins Nancy A, Steingrímsson Eiríkur
Abstract excerpt
The microphthalmia-associated transcription factor (Mitf) has emerged as an important model for gene regulation in eukaryotic organisms. In vertebrates, it regulates the development of several cell types including melanocytes and has also been shown to play an important role in melanoma. In vitro...
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