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Article

Distinct distal regulatory elements control tyrosinase expression in melanocytes and the retinal pigment epithelium.

Developmental biology - 15 Mar 2007

Murisier Fabien, Guichard Sabrina, Beermann Friedrich

Abstract excerpt

Pigment cells of mammals are characterized by two different developmental origins: cells of the retinal pigment epithelium (RPE) originate from the optic cup of the developing forebrain, whereas melanocytes arise from the neural crest. The pigmentation gene tyrosinase is expressed in all pigment cells but differentially regulated in melanocytes and RPE. The tyrosinase promoter does not confer strong expression in...

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Source

Identifiers

PMID: 17196956
DOI: 10.1016/j.ydbio.2006.11.038

Genes

RPE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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