Article
A conserved transcriptional enhancer that specifies Tyrp1 expression to melanocytes.
Developmental biology - 15 Oct 2006
Murisier Fabien, Guichard Sabrina, Beermann Friedrich
Abstract excerpt
Pigment cells of mammals originate from two different lineages: melanocytes arise from the neural crest, whereas cells of the retinal pigment epithelium (RPE) originate from the optic cup of the developing forebrain. Previous studies have suggested that pigmentation genes are controlled by different regulatory networks in melanocytes and RPE. The promoter of the tyrosinase-related family gene Tyrp1 has been shown...
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