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Article

Phagocytic receptor CED-1 initiates a signaling pathway for degrading engulfed apoptotic cells.

PLoS biology - 18 Mar 2008

Yu Xiaomeng, Lu Nan, Zhou Zheng

Abstract excerpt

Apoptotic cells in animals are engulfed by phagocytic cells and subsequently degraded inside phagosomes. To study the mechanisms controlling the degradation of apoptotic cells, we developed time-lapse imaging protocols in developing Caenorhabditis elegans embryos and established the temporal order of multiple events during engulfment and phagosome maturation. These include sequential enrichment on phagocytic...

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Identifiers

PMID: 18351800
DOI: 10.1371/journal.pbio.0060061
PMCID: PMC2267821

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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