Article
C. elegans Rab GTPase 2 is required for the degradation of apoptotic cells.
Development (Cambridge, England) - 1 Mar 2008
Lu Qun, Zhang Yan, Hu Tianjing, Guo Pengfei, Li Weida, Wang Xiaochen
Abstract excerpt
During apoptosis, the dying cell activates an intrinsic mechanism that quickly dismantles itself. The apoptotic cell corpses are then recognized and removed by neighboring cells or professional phagocytes. How dying cells are degraded after internalization is poorly understood. Here, we report the identification and characterization of unc-108, the Caenorhabditis elegans homolog of the human Rab GTPase 2, as a...
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