Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phagocytic receptor signaling regulates clathrin and epsin-mediated cytoskeletal remodeling during apoptotic cell engulfment in C. elegans.

Development (Cambridge, England) - 1 Aug 2013

Shen Qian, He Bin, Lu Nan, Conradt Barbara, Grant Barth D, Zhou Zheng

Abstract excerpt

The engulfment and subsequent degradation of apoptotic cells by phagocytes is an evolutionarily conserved process that efficiently removes dying cells from animal bodies during development. Here, we report that clathrin heavy chain (CHC-1), a membrane coat protein well known for its role in receptor-mediated endocytosis, and its adaptor epsin (EPN-1) play crucial roles in removing apoptotic cells in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adaptor Proteins, Vesicular Transport
Share to Cytoskeleton

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dynamins

Share to Gene Knockdown Techniques

Share to Genes, Helminth

Share to Microfilament Proteins

Share to Phagocytes

Share to Pseudopodia

Source

Open in PubMed Open full text

Identifiers

PMID: 23861060
DOI: 10.1242/dev.093732
PMCID: PMC3931732

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phagocytic receptor signaling regulates clathrin and epsin-mediated cytoskeletal remodeling during apoptotic cell engulfment in C. elegans.PMID 23861060Read ↗

Phagocytic receptor CED-1 initiates a signaling pathway for degrading engulfed apoptotic cells.Semantic proximity Read ↗

C. elegans Dynamin mediates the signaling of phagocytic receptor CED-1 for the engulfment and degradation of apoptotic cells.Semantic proximity Read ↗

Live-cell imaging in Caenorhabditis elegans reveals the distinct roles of dynamin self-assembly and guanosine triphosphate hydrolysis in the removal of apoptotic cells.Semantic proximity Read ↗

The phosphoinositide phosphatase MTM-1 regulates apoptotic cell corpse clearance through CED-5-CED-12 in C. elegans.Semantic proximity Read ↗

Calcineurin regulates coelomocyte endocytosis via DYN-1 and CUP-4 in Caenorhabditis elegans.Semantic proximity Read ↗

Genetic analysis of endocytosis in Caenorhabditis elegans: coelomocyte uptake defective mutants.Semantic proximity Read ↗

Cell corpse engulfment mediated by C. elegans phosphatidylserine receptor through CED-5 and CED-12.Semantic proximity Read ↗

The plasma membrane calcium ATPase MCA-3 is required for clathrin-mediated endocytosis in scavenger cells of Caenorhabditis elegans.Semantic proximity Read ↗

Deciphering endocytosis in Caenorhabditis elegans.Semantic proximity Read ↗

GOP-1 promotes apoptotic cell degradation by activating the small GTPase Rab2 in C. elegans.Semantic proximity Read ↗

C. elegans Disabled is required for cell-type specific endocytosis and is essential in animals lacking the AP-3 adaptor complex.Semantic proximity Read ↗

C. elegans Rab GTPase activating protein TBC-2 promotes cell corpse degradation by regulating the small GTPase RAB-5.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.