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Article

Cell corpse engulfment mediated by C. elegans phosphatidylserine receptor through CED-5 and CED-12.

Science (New York, N.Y.) - 28 Nov 2003

Wang Xiaochen, Wu Yi-Chun, Fadok Valerie A, Lee Ming-Chia, Gengyo-Ando Keiko, Cheng Li-Chun, Ledwich Duncan, Hsu Pei-Ken, Chen Jia-Yun, Chou Bin-Kuan, Henson Peter, Mitani Shohei, Xue Ding

Abstract excerpt

During apoptosis, phosphatidylserine, which is normally restricted to the inner leaflet of the plasma membrane, is exposed on the surface of apoptotic cells and has been suggested to act as an "eat-me" signal to trigger phagocytosis. It is unclear how phagocytes recognize phosphatidylserine. Recently, a putative phosphatidylserine receptor (PSR) was identified and proposed to mediate recognition of...

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PMID: 14645848
DOI: 10.1126/science.1087641

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Cell corpse engulfment mediated by C. elegans phosphatidylserine receptor through CED-5 and CED-12.PMID 14645848Read ↗

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