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Article

Replacement of a Drosophila Polycomb response element core, and in situ analysis of its DNA motifs.

Molecular genetics and genomics : MGG - 1 Jun 2008

Kozma Gabriella, Bender Welcome, Sipos László

Abstract excerpt

Long-term repression of homeotic genes in the fruit fly is accomplished by proteins of the Polycomb Group, acting at Polycomb response elements (PREs). Here we use gene conversion to mutate specific DNA motifs within a PRE to test their relevance, and we exchange PREs to test their specificity. Previously we showed that removal of a 185 bp core sequence from the bithoraxoid PRE of the bithorax complex results in...

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PMID: 18350319
DOI: 10.1007/s00438-008-0336-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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