Analysis of the functional role of the Polycomb chromo domain in Drosophila melanogaster.

doi:10.1101/gad.6.7.1241

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Article

Analysis of the functional role of the Polycomb chromo domain in Drosophila melanogaster.

Genes & development - 1 Jul 1992

Messmer S, Franke A, Paro R

Abstract excerpt

The chromo domain was identified as a homologous protein motif between Polycomb (Pc)--a member of the Pc-group genes encoding transcriptional repressors of the homeotic genes--and HP1--a heterochromatin-associated protein encoded by the suppressor of position effect variegation gene Su(var)205. Together with previous genetic studies, this molecular similarity supports the suggestion of a common mechanism used for...

Topics

Alleles
Amino Acid Sequence
Animals
Base Sequence
Cell Nucleus
Cells, Cultured
Chromobox Protein Homolog 5
DNA
Drosophila Proteins
Drosophila melanogaster
Heterochromatin
Immunohistochemistry

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Insect Hormones

Molecular Sequence Data

Mutation

Nuclear Proteins

Nucleic Acid Hybridization

Polycomb Repressive Complex 1

Source

Open in PubMed

Identifiers

PMID: 1628830
DOI: 10.1101/gad.6.7.1241

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1628830-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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