Article
Polycomb group repression reduces DNA accessibility.
Molecular and cellular biology - 1 Oct 2001
Fitzgerald D P, Bender W
Abstract excerpt
The Polycomb group proteins are responsible for long-term repression of a number of genes in Drosophila melanogaster, including the homeotic genes of the bithorax complex. The Polycomb protein is thought to alter the chromatin structure of its target genes, but there has been little direct evidence for this model. In this study, the chromatin structure of the bithorax complex was probed with three separate assays...
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