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Article

A Polycomb response element in the Ubx gene that determines an epigenetically inherited state of repression.

The EMBO journal - 1 Jun 1994

Chan C S, Rastelli L, Pirrotta V

Abstract excerpt

Segmentation genes provide the signals for the activation and regulation of homeotic genes in Drosophila but cannot maintain the resulting pattern of expression because their activity ceases halfway through embryogenesis. Maintenance of the pattern is due to the Polycomb group of genes (Pc-G) and the trithorax group of genes (trx-G), responsible for the persistence of the active or repressed state of homeotic...

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Identifiers

PMID: 7912192
DOI: 10.1002/j.1460-2075.1994.tb06545.x
PMCID: PMC395129

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Research trail→

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A Polycomb response element in the Ubx gene that determines an epigenetically inherited state of repression.PMID 7912192Read ↗

From genetics to epigenetics: the tale of Polycomb group and trithorax group genes.Semantic proximity Read ↗

In situ dissection of a Polycomb response element in Drosophila melanogaster.Semantic proximity Read ↗

The Drosophila trithorax protein binds to specific chromosomal sites and is co-localized with Polycomb at many sites.Semantic proximity Read ↗

Probes of chromatin accessibility in the Drosophila bithorax complex respond differently to Polycomb-mediated repression.Semantic proximity Read ↗

A genetic screen identifies novel polycomb group genes in Drosophila.Semantic proximity Read ↗

A Polycomb and GAGA dependent silencer adjoins the Fab-7 boundary in the Drosophila bithorax complex.Semantic proximity Read ↗

A functionally conserved Polycomb response element from mouse HoxD complex responds to heterochromatin factors.Semantic proximity Read ↗

The Additional sex combs gene of Drosophila encodes a chromatin protein that binds to shared and unique Polycomb group sites on polytene chromosomes.Semantic proximity Read ↗

Drosophila chromosome condensation proteins Topoisomerase II and Barren colocalize with Polycomb and maintain Fab-7 PRE silencing.Semantic proximity Read ↗

Cellular memory of transcriptional states by Polycomb-group proteins.Semantic proximity Read ↗

Functional analysis of mouse Polycomb group genes.Semantic proximity Read ↗

A Polycomb domain found in committed cells impairs differentiation when introduced into PRC1 in pluripotent cells.Semantic proximity Read ↗

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